Tuberculosis8 March 2026 4 min read

TB in Hyderabad: 6 symptoms that need immediate testing

Dr. S.A. Rafi
Dr. S.A. Rafi
Consultant Pulmonologist · City Chest Clinic, Hyderabad

India accounts for roughly a quarter of the world’s tuberculosis cases, and Telangana carries a meaningful share of that burden. TB is entirely curable — but only if it is found. The tragedy we see in clinic is not untreatable disease; it is disease that was treated as "seasonal cough" for four months first.

The six symptoms that should trigger a test

  • Cough for more than two weeks, dry or with sputum. This alone is enough to justify a sputum test — you do not need to wait for anything else.
  • Evening or low-grade fever, often with drenching night sweats that soak the bedsheet or clothes.
  • Unintentional weight loss and loss of appetite over weeks to months.
  • Blood in the sputum, even a single streak. Never dismiss this.
  • Chest pain, or breathlessness on mild exertion.
  • Persistent fatigue and weakness out of proportion to your activity.

If you have had a cough for more than two weeks, get a sputum test. It is inexpensive, widely available, and free at every government DOTS centre in Hyderabad.

TB is not only a lung disease

Extra-pulmonary TB is common and presents quite differently, which is why it is so often missed.

  • Lymph node TB: painless, gradually enlarging swellings in the neck or armpit.
  • Pleural TB: fluid around the lung causing breathlessness and one-sided chest pain.
  • Spinal TB: persistent back pain with fever and weight loss, and in advanced cases weakness of the legs.
  • Abdominal TB: chronic abdominal pain, distension, altered bowel habit and weight loss.
  • TB meningitis: prolonged headache, fever, vomiting, neck stiffness and altered behaviour — a medical emergency.

Who is at higher risk

  • Close household or workplace contact with a known TB patient.
  • Diabetes — which roughly triples TB risk and is extremely common in Hyderabad. Every TB patient should be screened for diabetes and vice versa.
  • HIV infection, cancer treatment, long-term steroids, or immunosuppressive drugs for autoimmune disease.
  • Smoking, alcohol use, malnutrition, and chronic kidney or liver disease.
  • Crowded, poorly ventilated living or working conditions, and silica or dust exposure in stone-cutting, construction or mining work.

How TB is diagnosed today

Testing has improved enormously and results are much faster than most people assume.

  • CBNAAT / GeneXpert — a rapid molecular test on sputum that confirms TB and simultaneously detects rifampicin resistance, usually within two hours. This is now the recommended first test and it is available free in the public system.
  • Sputum smear microscopy — cheap and quick, but it misses a meaningful proportion of cases, so a negative smear does not exclude TB.
  • Chest X-ray — useful to see the extent of disease, but it cannot confirm TB by itself; many other conditions look similar.
  • Culture and drug susceptibility testing — the reference standard, and essential in suspected drug-resistant disease.
  • Bronchoscopy with lavage — used when the patient cannot produce sputum or when results are negative but suspicion remains high. This is performed at the clinic where indicated.
  • Biopsy, pleural fluid analysis or CT-guided sampling for extra-pulmonary disease.

Treatment: and the mistake that creates drug-resistant TB

Standard drug-sensitive pulmonary TB is treated for six months: an intensive phase of four drugs for two months, followed by a continuation phase. The great majority of patients feel substantially better within three to four weeks — and that is precisely where the danger lies.

Feeling better does not mean the bacteria are gone. Stopping early, or taking doses irregularly, kills the susceptible organisms and allows the resistant ones to multiply. That is how multidrug-resistant TB is created, and MDR-TB requires far longer treatment with harsher drugs and a considerably worse outcome. Every single dose, for the full duration, matters.

  • Complete the entire course even after symptoms disappear.
  • Expect orange-red urine on rifampicin — this is harmless and expected.
  • Report jaundice, persistent vomiting, severe joint pain, visual changes, skin rash or numbness and tingling promptly, as the regimen may need adjustment.
  • Have your blood sugar, HIV status, liver function and weight monitored during treatment.
  • Ensure household contacts are screened, and that eligible contacts receive preventive therapy.
  • Cover your mouth when coughing, and keep rooms well ventilated with open windows. After two weeks of effective treatment, infectiousness falls dramatically.

Nutrition matters more than people think

Undernutrition is the largest single risk factor for TB in India. Adequate protein and calories improve treatment response and reduce relapse. Eligible patients also receive nutritional support under the national Ni-kshay Poshan Yojana scheme — ask about registration.

Frequently asked questions

Is TB curable?

Yes. Drug-sensitive TB is cured in over 90% of patients who complete the full six-month course. Even multidrug-resistant TB is curable, but it needs longer treatment with a specialised regimen.

How long am I infectious?

Infectiousness drops sharply after roughly two weeks of effective treatment. Until then, cover your mouth when coughing, keep rooms well ventilated, and avoid close contact with infants, elderly and immunocompromised people.

Do family members need to be tested?

Yes. All household contacts should be screened, and children under five as well as other eligible contacts should be assessed for TB preventive therapy. This is one of the most effective ways to interrupt transmission.

Where can I get tested for TB in Hyderabad?

Sputum CBNAAT testing is available free at government DOTS centres across Hyderabad. For a full pulmonology evaluation — including chest imaging, bronchoscopy where sputum is negative, drug-resistance assessment and treatment supervision — consult Dr. S.A. Rafi at City Chest Clinic, Mehdipatnam, on +91 81215 09229.

Medical disclaimer: This article is for general education and is not a substitute for a personal consultation. Do not start, stop or change any medication on the basis of this page. For advice specific to you, consult Dr. S.A. Rafi at City Chest Clinic, Mehdipatnam, Hyderabad.

Dr. S.A. Rafi
Dr. S.A. Rafi
Chief Consultant Interventional Pulmonologist & Sleep Specialist

20+ years of pulmonology practice in Hyderabad. Director of City Chest Clinic, Mehdipatnam and Senior Consultant Pulmonologist at KIMS Hospitals, Gachibowli.

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